Postoperative SIRS/sepsis: Dx

Sepsis is an infection-induced syndrome defined as the presence of two or more manifestations of a systemic inflammatory response syndrome (SIRS). SIRS includes:

1. Body temp greater than 38 C or less than 36 C.
2. HR > 90/min.
3. RR> 20/min or PaCO₂ < 32mmHg.
4. Leukocytosis (>12×109/L (>12,000/mm³)) or leukopenia (<4×109/L (<4000/mm³)).
5. Mechanical control of ventilation is continued in postop period if hemodynamic instability or if inotropic support is needed.