Transitioning to Inclusivity in OB Anesthesia
May 2025 Fellows Webinar Series
Approaches to the Thoracic Paravertebral Block with Dr. Melody Anderson (Herman)
May 2025 episode of OA-Regional Anesthesia Block of the Month now available!
3 new episodes of PAINTS now available!
Topics include writing an abstract, conflicts, and error reporting.
Five Tips for Managing the Pediatric Difficult Airway
New vodcast series: OA Pediatric Tip of the Month!
Check out the latest OpenAnesthesia Summaries!
More than 400 mini-reviews on high-yield topics in anesthesiology, critical care, and perioperative medicine.
Question of the Day
Which of the following BEST explains the anti-platelet effect of clopidogrel (Plavix) and ticlopidine (Ticlid)?
Explanation
Clopidogrel (Plavix) and ticlopidine (Ticlid) inhibit adenosine diphosphate (ADP) receptors, specifically P2Y12 receptors. Aspirin irreversibly inhibits blocks cyclooxygenase leading to a reduction in the formation of thromboxane A2 in platelets, which produces an inhibitory effect on platelet aggregation. Abciximab (ReoPro), eptifibatide (Integrilin), and tirofiban (Aggrastat) inhibit Glycoprotein IIB/IIIA receptors. All the Glycoprotein IIB/IIIA receptor blockers are only available intravenously. Dipyridamole (Persantine) is a phosphodiesterase inhibitor; however, it also blocks adenosine reuptake.
