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Summary of the Day
Spinal Anesthesia in Adults: Pharmacology, Technique, and Side Effects
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Question of the Day
Clopidogrel (Plavix) exerts its antiplatelet effect through which of the following mechanisms?
Explanation
Clopidogrel (Plavix) functions through ADP receptor inhibition. Drugs such as abciximab (ReoPro), eptifibatide (Integrilin), inhibit Glycoprotein IIb/IIIa. Postocyclin analogues (epoprostenol) have weak antiplatelet effects and are normally used in the treatment of pulmonary hypertension. Aspirin and NSAIDs function through cyclooxygenase inhibition, blocking thromboxane A2 formation.
References:
Antiplatelet Agents
