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Summary of the Day

Work of breathing: Neonate vs. adult

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Question of the Day

How many colony-forming units are required from a quantitative bronchoalveolar lavage (BAL) to make the diagnosis of pneumonia?

1,000 CFU/mL

100,000 CFU/mL

1,000,000 CFU/mL

10,000 CFU/mL

Your Anwser

Correct Anwser

Explanation

The cutoff point used for the diagnosis of pneumonia is 10,000 CFU/mL for BAL (for endotracheal aspirates the cutoff is 1,000,000 CFU/mL, and for a protected brush specimen the cutoff is 1,000 CFU/mL). Diagnosing a pneumonia with less than 10,000 CFU/mL based on a BAL runs the risk of inappropriately administering antibiotics, and theoretically runs the risk of increased antimicrobial resistance.

References:

Pneumonia