Perioperative Respiratory Adverse Events in Pediatric Patients
OA-SPA Ask the Expert - May 2024
Perioperative Care of Neurodiverse Patients
OA-SPA Pediatric Virtual Grand Rounds - Summer 2024
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Question of the Day
Which of the following is MOST likely to result from prone positioning in ARDS?
Explanation
Prone position is typically associated with improved oxygenation, a lower FRC, and a better drainage of secretions. Initial data from Gattinoni's trial and the Prone-Supine II Study Group suggested improved oxygenation but no improvement in mortality with prone positioning. More recently, the ProSeva trial (n = 466) challenged these results, demonstrating a large reduction in the mortality of patients with severe ARDS.
References:
Guérin C, Reignier J, Richard JC, et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med. 2013;368(23):2159-2168. doi:10.1056/NEJMoa1214103 Taccone P, Pesenti A, Latini R, et al. Prone positioning in patients with moderate and severe acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2009;302(18):1977-1984. doi:10.1001/jama.2009.1614 ARDS: Prone position mechanism
OA Series: May 2024
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